IL-6 predicts organ dysfunction and mortality in patients with multiple injuries
نویسندگان
چکیده
منابع مشابه
IL-6 predicts organ dysfunction and mortality in patients with multiple injuries
BACKGROUND Although therapeutic concepts of patients with major trauma have improved during recent years, organ dysfunction still remains a frequent complication during clinical course in intensive care units. It has previously been shown that cytokines are upregulated under stress conditions such as trauma or sepsis. However, it is still debatable if cytokines are adequate parameters to descri...
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Background: Interleukin 6 (IL-6) functions as both a pro-inflammatory cytokine and an anti-inflammatory cytokine. Objective: To evaluate the levels of IL-6 in patients with multiple organ dysfunction syndrome (MODS). Methods: Level of IL-6 was assessed and recorded for 14 days subsequent to the injury in 161 multiple trauma patients. MODS were diagnosed using Marshal Score. Injury Severity Scor...
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OBJECTIVE Multiple organ dysfunction syndrome (MODS) is the sequential failure of several organ systems after a trigger event, like sepsis or cardiogenic shock. Mortality rate is high, up to 70%. Autonomic dysfunction may substantially contribute to the development of MODS. Our study aimed to characterize a) the spectrum of autonomic dysfunction of critically ill MODS patients; b) whether auton...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
سال: 2009
ISSN: 1757-7241
DOI: 10.1186/1757-7241-17-49